视网膜短链脱氢酶/还原酶家族7抗体说明书

产品名称：视网膜短链脱氢酶/还原酶家族7抗体

浓度：1mg/1ml

规格：0.2ml/200μg         

抗体来源：Rabbit 

克隆类型：polyclonal

交叉反应：Human, Mouse, Rat, Rabbit  

产品类型：视网膜短链脱氢酶/还原酶家族7抗体一抗   

研究领域：细胞生物 免疫学 发育生物学 神经生物学 

蛋白分子量：predicted molecular weight: 35kDa

性状：Lyophilized or Liquid

免疫原：KLH conjugated synthetic peptide derived from human DHRS7

亚型：IgG

纯化方法：affinity purified by Protein A

储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用：WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user. 

保存条件：Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍：DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Similarity : Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Database links : UniProtKB/Swiss-Prot: Q9Y394.1