短链脱氢还原酶13抗体说明书

产品名：短链脱氢还原酶13抗体
别名：Dehydrogenase/reductase (SDR family) member 13; Dehydrogenase/reductase SDR family member 13; DHRS 13; MGC23280; OTTHUMP00000163522; SDR7C5; Short chain dehydrogenase/reductase family 7C member 5; DHR13_HUMAN. 
浓度：1mg/1ml 
规格：0.2ml/200μg          
抗体来源：Rabbit  
克隆类型：polyclonal 
交叉反应：Human, Mouse, Rat, Cow, Horse, Sheep   
产品类型：短链脱氢还原酶13抗体一抗    
研究领域：细胞生物 免疫学 发育生物学 神经生物学  
蛋白分子量：predicted molecular weight: 38kDa 
性状：Lyophilized or Liquid 
免疫原：KLH conjugated synthetic peptide derived from human DHRS13 
亚型：IgG 
纯化方法：affinity purified by Protein A 
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
产品应用：WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.  

保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍：DHRS13 (dehydrogenase/reductase SDR family member 13), also known as UNQ419/PRO853, is a 377 amino acid secreted protein belonging to the short-chain dehydrogenases/reductases (SDR) family. DHRS13 is presumed to function as an oxidoreductase and is phosphorylated, potentially by ATM or ATR, upon DNA damage. DHRS13 exists as two isoforms produced by alternative splicing events. The gene encoding DHRS13 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Neurofibromatosis, dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are associated with chromosome 17.

Function : Putative oxidoreductase (Potential). 

Subcellular Location : Secreted (Potential). 

Post-translational modifications : Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity). 

Similarity : Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Database links : UniProtKB/Swiss-Prot: Q6UX07.1