防御素β2抗体试验方法

英文名称    beta 2 Defensin   

中文名称    防御素β2抗体   

别    名    BD 2; BD-2; BD2; beta 2; Beta defensin 2; Beta-defensin 2; Beta-defensin 4A; DEF B2; DEF B4; DEFB 102; DEFB 2; DEFB 4; DEFB102; DEFB2; DEFB4; DEFB4B; Defensin; Defensin beta 2; Defensin beta 4; DFB4A_HUMAN; HBD 2; hBD-2; HBD2; SAP 1; SAP1 antibody Skin antimicrobial peptide 1; Skin-antimicrobial peptide 1.   

供应商      远慕生物

研究领域    细胞生物  发育生物学  细胞膜蛋白     

抗体来源    Rabbit   

克隆类型    Polyclonal   

交叉反应    Human,    

产品应用    ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 防御素β2抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.   

分 子 量    4kDa   

细胞定位    分泌型蛋白    

性    状    Lyophilized or Liquid   

浓    度    1mg/1ml   

免 疫 原    KLH conjugated synthetic peptide derived from human beta 2 Defensin   

亚    型    IgG   

纯化方法    affinity purified by Protein A   

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4   

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.   

防御素β2抗体产品介绍    background:

Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways

Function:
Has antibacterial activity.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in the skin and respiratory tract.

Similarity:
Belongs to the beta-defensin family. LAP/TAP subfamily.