DGCR2蛋白抗体使用说明书

英文名称    DGCR2    
中文名称    DGCR2蛋白抗体    
别    名    DGS C; DGS2; DiGeorge syndrome critical region gene 2; IDD; integral membrane protein DGCR2; LAN; SEZ 12.    
说 明 书    0.1ml  0.2ml      
研究领域    心血管  细胞生物  免疫学  神经生物学      
抗体来源    Rabbit    
克隆类型    Polyclonal    
交叉反应    Human, Mouse, Rat, Cow, Rabbit, Zebrafish, xenopuslaevisorangutan    
产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500DGCR2蛋白抗体 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    
分 子 量    59kDa    
细胞定位    细胞膜     
性    状    Lyophilized or Liquid    
浓    度    1mg/1ml    
免 疫 原    KLH conjugated synthetic peptide derived from human DGCR2    
亚    型    IgG    
纯化方法    affinity purified by Protein A    
储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    
保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.      
PubMed    PubMed    

DGCR2蛋白抗体产品介绍    background:
The DGCR2 gene encodes a novel putative adhesion receptor protein, which may play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22.

Function:
Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration. 
Subcellular Location:
Membrane; Single pass type I membrane protein.
Tissue Specificity:
Predominantly expressed in brain, heart, lung and fetal kidney. Low levels in liver and adult kidney. 

Similarity:
Contains 1 C-type lectin domain. 
Contains 1 LDL-receptor class A domain. 
Contains 1 VWFC domain. 
Database links:
UniProtKB/Swiss-Prot: P98153.1