醛固酮合成酶cyp11b2产品介绍

抗体名：醛固酮合成酶cyp11b2
英文名：anti-cyp11b2
研究领域：心血管  细胞生物  免疫学  
抗体来源：Rabbit
克隆类型：Polyclonal
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user。
分 子 量：52kDa
细胞定位：细胞浆 细胞膜
性：状：Lyophilized or Liquid
浓：度：1mg/1ml
免 疫 原：KLH conjugated synthetic peptide derived from human CYP11B2：
亚：型：IgG
纯化方法：affinity purified by Protein A：
储 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

产品介绍：background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008].

Function:
Preferentially catalyzes the conversion of 11-deoxycorticosterone to aldosterone via corticosterone and 18-hydroxycorticosterone.

Subcellular Location：
Mitochondrion membrane.